ALB and coronary artery disorder: In contrast, an inverse relationship between serum albumin and the incidence of coronary heart disease was observed among individuals with serum cholesterol levels ≥250 mg/dl in a 5-year follow-up study of 820 Dutch men aged 64 to 84 years.29 Interestingly, in the NIPPON DATA80 cohort, a combination of low albumin (≤4.3 g/dl) and above-average TC (≥185 mg/dl) was associated with excess mortality among participants aged 30 to 59 years.30 Thus, the interaction between serum albumin and serum cholesterol levels may be affected by the age of the surveyed population.