EZR and pancreatic neoplasm: Ezrin was not detectable in normal pancreatic ducts and acini (Figure 7A); however, 64 PDAC samples were found to be ezrin positive (91.4%, 64/70) (Figure 7B-D, Table 2), suggesting that ezrin was overexpressed in human PDAC and that ezrin expression was likely associated with pancreatic cancer development.