PIK3C2A and myositis disease: The classic diagnostic criteria for dermatomyositis described by Bohan included 1) skin lesions (heliotropic rash, gottron paules); 2) proximal muscle weakness of upper or lower extremities; 3) elevated CPK and 4) aldolase levels; 5) myalgias; 6) abnormal electromyography; 7) positive anti-Jo-1 antibody; 8) nondestructive arthralgias; 9) systemic inflammatory signs; and 10) Myositis [3-5].