Meanwhile, approximately half of men over age 50 have received a prostate-specific antigen (PSA) test in their lifetime [3] and men between the ages of 50 to 69 are two- to three-times more likely to be screened for prostate cancer than colorectal cancer, even though PSA testing is not generally recommended in Canada [4]. The gene discussed is KLK3; the disease is prostate carcinoma.