LGALS3 and cancer: The reduction of metastasis-associated survival of nude mice intravenously injected with galectin-3-pretreated than untreated MUC1-expressing human melanoma cells observed in our earlier study [27] likely represents the consequence of galectin-3-MUC1 interaction on cancer cell heterotypic adhesion to endothelium as well as on cancer cell homotypic aggregation.