LGALS3 and cancer: We have previously shown that the interaction between cell surface MUC1 and galectin-3 at concentrations similar to those found in the sera of cancer patients increases cancer cell heterotypic adhesion to endothelium as a result of MUC1 cell surface polarization which leads to exposure of heterotypic cell-cell adhesion molecules that are otherwise concealed by elongated structure of MUC1 [12].