Although tumor-secreted VEGF-C/-D and, even VEGF-A to a lesser extent, are important for inducing intratumoral lymphangiogenesis in solid tumor mass [22], our results demontrated that ITLs in gastric cancer didn't be stimulated by VEGF-C/-D-mediated VEGFR-3 signaling pathway or VEGF-A expression. This evidence concerns the gene VEGFC and neoplasm.