In this context a preliminary comparative expression analysis of hTid, EGFR and ErbB-3 we have conducted in triple negative breast tumors and in cutaneous melanoma (data not shown) respectively also suggests an inverse correlation between the expression levels of hTid and the two receptors, thus, indicating that htid functional relation may indeed encompass other members of the EGFR family. This evidence concerns the gene ERBB3 and cutaneous melanoma.