Mice infected with CO92ΔyopH elicited a robust pro-inflammatory cytokine response at 24 h post-infection, characterized by 349 ± 43 pg/ml of TNF-α and 461 ± 35 pg/ml of IL-1β in the BALF of these mice 24 h post-infection (p = 0.001 in comparison to CO92). Here, TNF is linked to infection.