Efforts are currently on-going to identify Hsp90 clients in Brugia. Secondly, Hsp90 in tumor cells appears to have an increased affinity for drugs such as GA, a phenomenon which may relate to the conformation of Hsp90 in multi-chaperone complexes in tumor cells compared to normal cells, where it exists in a free uncomplexed state [22]. Here, HSP90AA1 is linked to neoplasm.