YKL-40 (alternatively called HCgp39 or CHI3L1) is observed in elevated levels for patients with severe asthma [91], cardiovascular disease and diabetes [92], cancer [93], peritoneal endometriosis [94], morbid obesity [95], osteoarthritis [96], and liver fibrosis [97]. The gene discussed is CHI3L1; the disease is morbid obesity.