In addition, urinary IL-8 levels can discriminate between superficial bladder cancer (SBC) and muscle invasive bladder cancer (MIBC) [5]; however, low assay sensitivity (62%) suggests urinary IL-8 is not a good marker for early diagnosis of bladder cancer, but may serve as a predictor of prognosis [5]. Here, CXCL8 is linked to urinary bladder cancer.