CRP and acute pyelonephritis: A positive correlation was shown between serum and urine levels of IL-6, IL-8, and C-reactive protein (CRP), WBC and fever in children with acute pyelonephritis [8].IL-8 levels in serum has 81% sensitivity and 78% specificity for the diagnosis of acute pyelonephritis, while, urine IL-8 levels showed 83% sensitivity and 83% specificity [8].