TCF7L2 and type 2 diabetes mellitus: Our results further demonstrated that rs7903146 in the TCF7L2 gene was significantly associated with T2D in the Han Chinese population in mainland China; the T risk allele of rs7903146 conferred a 1.58 fold increasing the likelihood of having T2D, as compared with individuals who do not carry any of the four risk alleles (adjusted p = 1.0 × 10-3, dominant model).