The alleles that differed among melanoma patients were HLA-A*03, HLA-B*037, *53, *54, *58, *59, *78, HLA-DRB1*1102, HLA-DQB1*0201, and *0302 with corresponding P values .042, .033, .050, .046, .001, .021, .004, .021, .006 and .033, respectively. This evidence concerns the gene HLA-A and melanoma.