Likewise, other class I alleles such as A*11, or class II alleles such as HLA-DQ1, an allele related to the susceptibility to autoimmune diseases,28 initially found to be associated with clinical response and survival with IL-2 therapy in the metastatic setting,9,10 were not found to be related to absence of recurrence in our group of patients. The gene discussed is IL2; the disease is autoimmune disease.