CITED2 and familial atrioventricular septal defect: Mice null for Cited2 die in utero from phenotypically heterogeneous cardiac malformations including atrial, ventricular, and atrioventricular septal defects (ASD, VSD, AVSD); outflow tract defects (double-outlet right ventricle [DORV], common arterial trunk [CAT], tetralogy of Fallot [TOF], transposition of great arteries [TGA]); and interrupted and right-sided aortic arch (Bamforth et al., 2001, 2004; Yin et al., 2002; Weninger et al., 2005).