Because our affected mice showed generalized amyloidosis, we concentrated on the amyloid related genes located in this region which included Saa1l (serum amyloid A-like 1), Saa3 (serum amyloid A 3), Saa4 (serum amyloid A 4), Saa1 (serum amyloid A 1), Saa2 (serum amyloid A 2) and Zdhhc13 (zinc finger, DHHC domain containing 13). The gene discussed is SAA4; the disease is amyloidosis.