CCL2 and central nervous system cancer: Experimental and clinical studies have shown that monocyte chemoattractant peptide-1 (MCP-1), also known as chemokine (C-C motif) ligand 2 (CCL2), is perhaps the chemokine most frequently expressed by tumor cells and is correlated with recruitment of host macrophages to the tumor site in a variety of human tumors, such as sarcomas, gliomas, melanomas, cancers of the breast, cervix, and ovary [6], [7].