ESR1 and neoplasm: Other independent variables including tumor size (OR per centimeter 1.244, 95% CI 1.182–1.310), pathology (OR 0.625, 95% CI 0.551–0.709), ER (OR of positive 0.645, 95% CI 0.566–0.735) and PR status (OR of positive 0.820, 95% CI 0.720–0.933), and HER2 status (OR of positive 1.363, 95% CI 1.167–1.591) had significant relationships with LN involvement.