Furthermore, the frequency of the CXCR2 (+1208) T allele was significantly higher in patients with a large tumor size (OR = 1.98; P = 0.0001), with high SBR tumor grade (grade 3) (OR = 1.67; P = 0.01), and with lymph node metastases (OR = 1.83; P = 0.0008). Here, CXCR2 is linked to neoplasm.