IL5 and Increased total eosinophil count: Giving an antibody to block interleukin-5, a regulator of eosinophilopoiesis, eosinophil migration, and eosinophil survival, eliminated both blood and airway lumen eosinophilia [102] but had little effect on airway wall eosinophils [103], and no pro-apoptotic effect has been demonstrated.