Although these medications were often used to treat specific symptoms or concomitant medical illness (e.g., biperiden for EPS; insulin or glibenclamide for elevated blood glucose; enalapril, captopril, propranolol, or magnesium sulphate for hypertension; antibiotics for infection; benzodiazepines or other tranquilizers for agitation), some (e.g., lucetam and cerebrolysin in one case) appear to have been given prophylactically. This evidence concerns the gene INS and hypertensive disorder.