The angiotensin converting enzyme (ACE) inhibitors have been known to induce a regression of the proteinuria both in normotensive and hypertensive patients with diabetic renal illness[8] and in hypertensive patients with chronic renal failure.[9] Calcium Channel Blockers (CCB) have only been evaluated recently with regard to their anti-proteinuric effects in humans with diabetes mellitus. This evidence concerns the gene ACE and diabetes mellitus.