BMPR2 and pulmonary arterial hypertension: Whereas Austin and colleagues [10] showed that PAH patients with missense mutations in BMPR2 gene had more severe disease than patients with truncating mutation with a significant younger age at diagnosis and a shorter survival from diagnosis to death or lung transplantation, we did not find any influence of mutation type on disease pattern or natural history among patients with BMPR2 mutation in the French PAH network.