If the rhodopsin/Arr1 complex contributed to the severe retinal degeneration in the light-exposed transgenic Q344terrho+/− background (Fig. 5A), we would expect an amelioration of the retinal morphology in the light-exposed transgenic retinas when Q344ter is expressed in the RK−/−, Trα−/− genetic background. This evidence concerns the gene ARRB1 and retinal degeneration.