CD8A and infection: Moreover, examination of fucosyltransferase-VII and-IV double knockout mice (FtDKO) for immunity following infection with Mycobacterium tuberculosis found that FtDKO mice had significantly diminished numbers of activated CD8 and CD4 T cells in the draining lymph node of the lung (mediastinal lymph node, MedLN), but had effective granuloma responses and similar recruitment of activated T cells into the lung at later stages of infection [21].