To test the hypothesis that altered expression of centrosome-related proteins may contribute to glioma grade, we analyzed the expression levels of centrosome regulatory proteins, such as Aurora A, and the chromosomal passenger protein, Aurora B, as well as centrosome structural proteins, including centrins 1 and 2, γ-tubulin, and hNinein in 34 glioma samples. Here, INCENP is linked to central nervous system cancer.