HMOX1 and supranuclear palsy, progressive, 1: Immunohistochemical staining for HO-1, BVR and H-ferritin in lung biopsies was significantly higher for PSP-S than PSP-NS and C patients (p<0.03; Figure 3), with both increased staining intensity per macrophage and increased number of positive-stained macrophages (Figure 3 and Table 1, p<0.03).