HIF1A and supranuclear palsy, progressive, 1: By contrast, HIF-1α protein expression in both the cytosol and nucleus of alveolar macrophages (CD68-positive cells) was higher in PSP-S tissue than in PSP-NS and C tissue, with no difference in expression between PSP-NS and C groups (Figure 5, p = 0.003 for the quantification of nuclear localization between PSP-S vs. the 2 other groups).