These genes include Car8 (Carbonic anhydrase 8), a protein associated with proliferation and invasiveness of colon cancer cells [61], Zdhhc23 (Zinc finger, DHHC-type containing 23), a Nitric oxide synthase-binding and activation protein [62], Flvcr2 (Feline leukemia virus subgroup C cellular receptor family, member 2), a calcium-chelate transporter [63], and Amy2 (Amylase 2), an amylase that catalyzes the endohydrolysis of 1,4-alpha-D-glucosidic linkages in oligosaccharides. The gene discussed is CA8; the disease is colonic neoplasm.