Telomere length might be affected by several biological and lifestyle factors, including body mass index (BMI) [7], [30], [31], smoking [7], [32], homocysteine levels [33], cardiovascular disease risk factors [8], [9], [34]–[37], insulin levels or resistance [10], [38], [39], diagnosis of diabetes [40], [41], sleep duration [16], or physical inactivity [42]. The gene discussed is INS; the disease is diabetes mellitus.