Increases in IL-1α, IL-1β, IL-2 and CCL3 were seen upon infection with Mtb and elevated to a small extent in supernatants from infected IL-10−/− mice versus controls; little to no change was seen in supernatants of IL-12p70, IL-4, IL-5, IL-7, IL-9 and IL-13 upon Mtb infection and no difference between WT and IL-10−/− mice – any small differences were variable (Supporting Information Table 1). The gene discussed is IL1B; the disease is infection.