This is in line with our earlier finding that BA suppresses hedgehog target genes in hepatoblastoma, another embryonal tumour of early childhood (Eichenmuller et al, 2009b) and a study by Rzeski et al (2006), which recently described that BA decreases expression of BCL2, a gene, which is known to be transcriptionally activated by GLI2 (Regl et al, 2004). This evidence concerns the gene GLI2 and hepatoblastoma.