In 2004 Novakovic et al. [62] evaluated the significance of detectable expression of RNA for telomerase subunits hTR and hTERT in the plasma of 25 primary breast cancer patients, 29 patients with advanced malignant melanoma, 4 patients with advanced thyroid cancer (2 Hurthle cancers poorly differentiated, 1 papillary well differentiated and 1 anaplastic thyroid cancer) and 7 healthy volunteers. Here, TERC is linked to thyroid gland carcinoma.