It is also believed that deficiencies in the lymphatic drainage system hamper early recognition of tumor-specific antigens.1 Chronic stasis, thereby producing local changes in the lymphatic protein composition (decreased alpha-2 globulin fraction and increased albumin-globulin ratio) and delaying protein transportation from the interstitial space into the lymphatic tissue, might change the tissue antigenic composition and/or regional immunological competence.4-6. Here, ALB is linked to neoplasm.