In our system, the tissue distribution of kallistatin in control mice was determined at higher concentrations in livers (27.0 ± 7.3 ng/mg), lungs (12.1 ± 3.9 ng/mg), and a lower concentrations in tumor sites (7.0 ± 5.0 ng/mg) by using human kallistatin ELISA system. This evidence concerns the gene SERPINA4 and neoplasm.