Ang et al reported on patients with squamous cell carcinomas of the head and neck (SCCHN) as part of the correlative biomarker study, where the overall survival (OS) and disease-free survival (DFS) rates of patients with high EGFR-expressing SCCHN were highly significantly lower and the local recurrence (LR) relapse rate was significantly higher compared with those of patients with low EGFR-expressing SCCHN [44]. The gene discussed is EGFR; the disease is head and neck squamous cell carcinoma.