The results presented in figure 6B demonstrated that only the smaller TGFBI-derived fragments (TGFBI < 3 kDa) induced caspase 3/7 activity in both A549 and H1299 NSCLC cells, while supernatants containing proteins larger than 3 kDa in size, or those obtained from non-transfected cells, had no effect on caspase activity. This evidence concerns the gene CASP3 and non-small cell lung carcinoma.