In the early GWAS, common variants in IGF2BP2, CDKAL1, SLC30A8, HHEX, CDKN2A/B, FTO, and TCF2 loci were reported to increase the risk of T2D in Caucasians [1-6], and KCNQ1 was recently discovered as a new diabetogenic gene in Japanese samples [7]. This evidence concerns the gene HNF1B and type 2 diabetes mellitus.