The associations of 7 SNPs with T2D were observed, which included, as follows: CDKAL1-rs10946398 (OR, 1.27; 95% CI, 1.11-1.45; empirical p = 0.0008); IGF2BP2-rs4402960 (OR, 1.26; 95% CI, 1.08-1.47; empirical p = 0.003); SLC30A8-rs13266634(OR, 1.19; 95% CI,1.04-1.37; empirical p = 0.009); CDKN2A/B-rs10811661(OR, 1.22; 95% CI, 1.06-1.41; empirical p = 0.005); HHEX-rs5015480 (OR,1.20; 95% CI, 1.01-1.42; empirical p = 0.03); and KCNQ1-2237892 (OR, 1.37; 95% CI, 1.19-1.69; empirical p = 1.0 × 10-4). This evidence concerns the gene CDKAL1 and type 2 diabetes mellitus.