Except for the Li study [13] due to the lack of allelic frequencies, the data from other studies and the current study were included in this meta-analysis to improve the power in evaluating the collective evidence on the relationships of these nine genetic loci to T2D, especially HHEX, IGF2BP2, TCF2 FTO, and WFS1 genetic loci. The gene discussed is FTO; the disease is type 2 diabetes mellitus.