For example, in the Chinese Han population, the associations between single nucleotide polymorphisms (SNPs) at the HHEX, IGF2BP2, TCF2, and FTO loci with T2D were not consistently replicated [6,10-15], and the findings in previous studies involving Caucasians for SNPs at the WFS1 locus have not been confirmed [12]. The gene discussed is WFS1; the disease is type 2 diabetes mellitus.