This is partly due to the features of our study (e.g., small sample sizes, enriched subjects with earlier onset T2D, and older subjects without a family history of T2D in the control group) or the difference in the studied population in genetic background as observed for the TCF7L2 and KCNQ1 genes in previous reports [7,21,22]. This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.