On the epigenetic level, HpaII-restriction assays yielded no evidence for FANCC-, FANCF- or FANCG-silencing through CpG hypermethylation (Fig. 6B) and consistently, FANCC-, FANCF- and FANCG-mRNA was detectable in all 18 HCC samples (Fig. 6C). Here, FANCG is linked to hepatocellular carcinoma.