The adipokines with black lettering are those whose circulating levels are enhanced in obesity and whose total release by adipose tissue explants is enhanced in obesity: IL-6, IL-10, ACE, TGFβ1, ICAM-1, TNFα, IL-1β, PAI-1, and IL-8 that are released by nonfat cells. The gene discussed is IL1B; the disease is obesity disorder.