FGF2 and Miyoshi myopathy: Rajkumar et al. showed a gradual increase of bone marrow angiogenesis along the disease spectrum from monoclonal gammopathy of undetermined significance (MGUS) to smoldering MM, newly diagnosed MM, and relapsed MM [86], though the expression levels of VEGF, bFGF, and their receptors were similar among MGUS, smoldering MM, and newly diagnosed MM [87], suggesting that MVD increase in plasma cell neoplasias could be a function of chronology.