VEGFA and ovarian carcinoma: Indeed, FGF-2 was detected in vesicles shed by human hepatocarcinoma Sk-Hep1 cells [17, 18]; VEGF was found to be present in vesicles shed by human ovarian carcinoma cells [19] and in vesicles shed by neurons and astrocytes [20, 21]; angiogenin, IL-6, IL-8, VEGF, and TIMPs were found in vesicles shed by glioblastoma tumor cells [22].