CRP and atherosclerosis: While conventional risk factors clearly play a major role in the predisposition to MI, a significant number of young patients with ACS do not have any of the conventional risk factors, except for a family history of CAD.6 Furthermore, some previous studies have shown a correlation between C-reactive protein (CRP) and the presence of atherosclerosis,7 whereas others have not found a correlation.8 CRP might lose much if not all of its predictive value in both secondary and primary risk settings after adjustment for quantitative angiographic measures of CAD.