While conventional risk factors clearly play a major role in the predisposition to MI, a significant number of young patients with ACS do not have any of the conventional risk factors, except for a family history of CAD.6 Furthermore, some previous studies have shown a correlation between C-reactive protein (CRP) and the presence of atherosclerosis,7 whereas others have not found a correlation.8 CRP might lose much if not all of its predictive value in both secondary and primary risk settings after adjustment for quantitative angiographic measures of CAD. This evidence concerns the gene CRP and coronary artery disorder.