In the unifactorial analysis of multiple comparisons of medians according to Scheffé for CRP plasma levels, it was found that in each group, an F statistic value of 24.113 was obtained which showed a significant grade much lower than 0.05 (ca. 0.000), thereby demonstrating a statistically significant difference between CRP plasma levels of the patients grouped according to the clinical severity of their PAD. The gene discussed is CRP; the disease is peripheral arterial disease.