KCNH2 and spindle cell hemangioma: As concerns our first inference, the A-A-A-T/C-A-C-G haplotypes extending across a number of haplotype blocks defined in the CEU population (Utah residents in USA with Northern and Western European ancestry from the Centre d'Etude du Polymorphisme Humaine collection) of the International HapMap Project [42] (Figure 4b) towards the intergenic region 3'-downstream of HERG1 may be a part of even larger SCH-associated haplotypes that might be related with more than one gene (Figure 4a) and/or with the copy number variation (CNV) of ~125 kb of length (Variation 3711) in 7q36.1.