Finally, as the other two members of the ERG channels family, ERG3 and ERG2, which are known for their widespread expression in brain, are seemingly nervous system-specific [24] and form heterotetramers with ERG1 channels [45-48], we believe that HERG3 and HERG2 genes also need to be extensively studied in psychotic disorders. The gene discussed is KCNH2; the disease is psychotic disorder.