In this study, we reasoned that a particular mechanism (HERG1 channel blockade, for example) responsible for a prevailing adverse effect of antipsychotic drugs (acquired LQT in this case) is also likely to be one unique mechanism by which their therapeutic effects are mediated, and that, by inference, this might contribute to our understanding of the underlying mechanisms in SCH. Here, KCNH2 is linked to spindle cell hemangioma.