In case of normalization by RPL29 which was predicted as most stable single reference gene in NormFinder and most stable combination with HPRT1 in geNorm, the high-low pattern of RQ difference between normal and tumor (Figure 5A) was similar to RQ by HPRT1 though there were difference in three patients (Figure 5B). Here, HPRT1 is linked to neoplasm.