CDKN1A and neoplasm: Variables in the multivariate linear regression model initially included sex, age, BMI, family history of colorectal cancer, smoking status, disease stage tumor location, grade, mucinous component, signet ring cells, Crohn's-like reaction, peritumoral lymphocytic reaction, tumor infiltrating lymphocytes (TIL), CIMP, MSI, BRAF mutation, KRAS mutation, PIK3CA mutation, TP53 expression, CDKN1A expression, CTNNB1 score, PTGS2 expression, and FASN expression.