In addition, our tumor database has enabled us to include other molecular variables (such as CDKN1A expression, CTNNB1 score, PTGS2 expression, FASN expression, KRAS mutation, BRAF mutation and PIK3CA mutation, all of which have been related with MSI or CIMP), as well as clinical and pathologic variables. The gene discussed is BRAF; the disease is neoplasm.