IFNG and tuberculosis: In children with definite or probable TB and a positive IFN-γ ELISpot at presentation, there was a decrease in the proportion of children who had a positive IFN-γ response to individual antigens ESAT-6 and CFP-10 following six months of anti-tuberculous treatment (Chi square for trend: ESAT-6 p = 0.006, CFP-10 p = 0.001).