AIP mutation-positive families most commonly present with somato-troph, or with both somatotroph and lactotroph adenomas, but rarely other types of pituitary tumors can be observed [Daly et al., 2007; Iwata et al., 2007; Leontiou et al., 2008; Toledo et al., 2007; Vierimaa et al., 2006]. This evidence concerns the gene AIP and prolactin-producing pituitary gland adenoma.