PRKN and Parkinson disease: In addition, several families reported affected heterozygous family members of a homozygous proband creating a false impression of dominant inheritance and indicating a possible predisposition of PARK2 or PINK1 variants to PD (PARK2: [Maruyama et al., 2000; Munhoz et al., 2004; Tan et al., 2003]/PINK1: [Criscuolo et al., 2006; Djarmati et al., 2006; Hedrich et al., 2006a; Ibanez et al., 2006]).