Furthermore, ALDH− cells FACS-isolated from ALDH− derived tumours (designated as ALDH−/−) could form 2nd generation tumours with the same efficiency and similar lag-time (40–47days) before palpability, as ALDH+ cells isolated from ALDH+ derived tumours (designated as ALDH+/+) (Table 1). The gene discussed is LDHA; the disease is neoplasm.