Among the genes with significantly altered expression in Eef1a2 RNAi cells (Table 1) were those involved in tumor invasion (Tgfbr2, Mmp13, Itgal), proliferation (Pik3cg, Fosb, Fos, Mapk1, Flt3, Wnt1, Cdk6, Ccnd2), survival (Ifi202b, Tnfsf13b, Bcl2, Bcl2l1), and cytokine and interferon signaling (Jak2, Stat1, Stat2, Stat3, Irf2, Irf8, Socs3). Here, IRF8 is linked to neoplasm.